In doing this blog and thinking about this stuff, have you ever had any ideas for what kinds of tools (software, that is) that people could use to do things like share creative ideas in groups, create customer community, etc. etc.? |
One condition would be that the groupblog would adopt your style. Similar to how the headfirst books have the same style but different writers. If you join the 37signals blog where you put up highly visual articles, in a see of more textual posts, you will still stand out. |
After I initially commented I clicked the -Notify me when new feedback are added- checkbox and now every time a comment is added I get four emails with the identical comment. Is there any method you possibly can remove me from that service? Thanks! |
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Conserved signaling pathways that activate the mitogen-activated protein kinases (MAPKs) are involved in relaying extracellular stimulations to intracellular responses. The MAPKs coordinately regulate cell proliferation, differentiation, motility, and survival, which are functions also known to be mediated by members of a growing family of MAPK-activated protein kinases (MKs; formerly known as MAPKAP kinases). The MKs are related serine/threonine kinases that respond to mitogenic and stress stimuli through proline-directed phosphorylation and activation of the kinase domain by extracellular signal-regulated kinases 1 and 2 and p38 MAPKs. There are currently 11 vertebrate MKs in five subfamilies based on primary sequence homology: the ribosomal S6 kinases, the mitogen- and stress-activated kinases, the MAPK-interacting kinases, MAPK-activated protein kinases 2 and 3, and MK5. In the last 5 years, several MK substrates have been identified, which has helped tremendously to identify the biological role of the members of this family. Together with data from the study of MK-knockout mice, the identities of the MK substrates indicate that they play important roles in diverse biological processes, including mRNA translation, cell proliferation and survival, and the nuclear genomic response to mitogens and cellular stresses. In this article, we review the existing data on the MKs and discuss their physiological functions based on recent discoveries.
Cells recognize and resp |
Maybe the private blog is the way to go, though I suspect you'd need some time to get revved up for that. The pod/video angle sounds great, but that raises a lot of other questions. And it loses the immediacy that you enjoyed so long, which is one of the most unfortunate losses in all this. |
Kathy, the content you have graciously shared with us every once in a while is both inspiring and entertaining. And a blog is the perfect medium for this. A lot of the content is about your style and creative personality. Thus, I would rule out the community-based ideas. I would probably only read your stuff anyway. |
Take me for example. I could support Bachman, Cain, Palin, or Santorum. in no particular order. Others would choose fewer plus Paul. |
I’m not sure what you have against “The Five”. I mean, four of the five panel members are on the right. The only creep is Bob Beckel. I admit, his creepiness makes the show a bit harder to handle. But Greg Gutfeld makes up for it! I LOVE him!! Beckel will probably have a stroke or a heart attack on the show one day and they can just shove him off the stage and continue on. |
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